Saturday's flagship offer once again contains the three odds-on favourites among the 1500 GMT kick-offs in the top-flight and punters will be confident of hitting back after the layers emerged on top last weekend when none of Liverpool, Tottenham and Arsenal could win.
Chelsea arrive in top shape following their midweek cruise in the Champions League and will look to return to their Premier League best at home to Hull after suffering a first defeat of the campaign at Newcastle last weekend.
Manchester City should be on a high after reaching the knockout stages of the Champions League at Roma's expense on Wednesday and Manuel Pellegrini's side travel to basement-dwellers Leicester.
Southampton complete the treble as they face Burnley at Turf Moor. Ronald Koeman's men still occupy fifth place in the table despite three defeats on the spin and were arguably a shade unlucky to be beaten by Manchester United on Monday night. Can they get back on track in Lancashire?
MONEY BACK if Man United beat Liverpool on Super Sunday!
Sky Bet's head of trading Sandro Di Michele said: "Another huge weekend of football and another big offer as we once again give our customers the chance to back the teams they want to back at an enhanced price.
"We'll be looking for at least one of the favourites to slip up but the two big guns appear rock solid and we may have to hope Burnley can give Southampton a tough test."
Sky Bet also have a Money Back Offer for the big Super Sunday game between Manchester United and Liverpool - Money Back if United win.
All you have to do is place a minimum of £5/€5 and Sky Bet will refund losing first goalscorer, last goalscorer, correct score and scorecast singles (Price Boosts are not included in the eligible markets) as a free bet up to £25/€25 within 24 hours if Louis van Gaal's side get the better of of their bitter rivals.
Soccer Saturday Price Boost
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